Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online:957
  • Home
  • Print this page
  • Email this page
Year : 2017  |  Volume : 31  |  Issue : 1  |  Page : 23-27

Postoperative pain relief using intrathecal morphine for lumbar spine decompression and instrumentation surgery: A comparative study of two different doses

Department of Anaesthesiology, Dr. B. L. Kapur Memorial Hospital, New Delhi, India

Correspondence Address:
Priyanka Dhir
B-6, Shankar Garden, New Delhi - 110 018
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijpn.ijpn_22_17

Rights and Permissions

Background and Aims: Patients undergoing lumbar spine instrumentation surgery suffer severe postoperative pain which is difficult to treat by conventional multimodal analgesic methods. We aimed to compare the analgesic effect of two different doses of intrathecal morphine (ITM) 0.2 mg and 0.3 mg in patients undergoing lumbar spine decompression and instrumentation surgery. Design: This was a randomized, prospective, double-blinded study. Materials and Methods: After approval from the Institutional Ethics Committee, forty American Society of Anesthesiologists 1 and 2 patients of either sex aged 18 years or older undergoing lumbar spine surgery were randomly assigned to receive ITM either 0.2 mg (Group A, n = 20) or 0.3 mg (Group B, n = 20) in 2 ml saline before general anesthesia. A morphine intravenous patient-controlled analgesia (PCA) device was used for rescue analgesia in the postoperative period. Assessment parameters included hemodynamics, sedation score, pain using numeric rating scale (NRS), total consumption of PCA morphine recorded for 24 h, and patient's satisfaction score. The data were analyzed using Chi-square test for categorical variables and Student's t-test for quantitative variables. Results: NRS score was significantly low in Group B at 4, 8, 12, and 24 h as compared to Group A (P < 0.05). Group B also had decreased requirement for rescue analgesia (P = 0.001) with higher patient satisfaction. There was no significant difference between the two groups in other studied parameters. Conclusions: 0.3 mg ITM provided superior analgesia postoperatively in terms of NRS score and higher patient satisfaction compared to 0.2 mg with no significant difference in the incidence of side effects.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded194    
    Comments [Add]    

Recommend this journal