Indian Journal of Pain

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 28  |  Issue : 1  |  Page : 36--41

Addition of Clonidine or Dexmedetomidine to Ropivacaine prolongs caudal analgesia in children


Shobhana Gupta1, Virendra Pratap2 
1 Department of Anaesthesiology, Gujarat Medical Education and Research Society Medical College, Gandhinagar, Gujarat, India
2 M. P. Shah Medical College, Jamnagar, Gujarat, India

Correspondence Address:
Shobhana Gupta
Block No.105, Sector 8B, Gandhinagar - 382 010, Gujarat
India

Background: Caudal block is a common technique for pediatric analgesia, but with the disadvantage of short duration of action after single injection. We compared the analgesic effects and side-effects of dexmedetomidine and clonidine added to ropivacaine in pediatric patients undergoing lower abdominal surgeries. Materials and Methods: A study was conducted among 60 pediatric patients undergoing lower abdominal surgeries. A total of 60 American Society of Anesthesiologists (ASA) status I and II pediatric patients between the age of 1 and 6 years were enrolled in this study. The caudal block was administered with inj. ropivacaine 0.2% with clonidine 2 μg/kg (group A) and inj. ropivacaine 0.2% with dexmedetomidine 2 μg/kg (group B) after induction with general anesthesia. Hemodynamic parameters were observed before, during, and after the surgical procedure. Postoperative analgesic duration, total dose of rescue analgesia, pain scores, and any side effects were looked for and recorded. Results: Addition of dexmedetomidine or clonidine to caudal ropivacaine significantly promoted analgesic time. Also, there was statistically significant difference between dexmedetomidine and clonidine as regard to duration of analgesia. No significant difference was observed in incidence of hemodynamic changes or side effects. Conclusions: Addition of dexmedetomidine or clonidine to caudal ropivacaine significantly promoted analgesia in children undergoing lower abdominal surgeries with significant advantage of dexmedetomidine over clonidine and without an increase in incidence of side-effects.


How to cite this article:
Gupta S, Pratap V. Addition of Clonidine or Dexmedetomidine to Ropivacaine prolongs caudal analgesia in children.Indian J Pain 2014;28:36-41


How to cite this URL:
Gupta S, Pratap V. Addition of Clonidine or Dexmedetomidine to Ropivacaine prolongs caudal analgesia in children. Indian J Pain [serial online] 2014 [cited 2020 Aug 9 ];28:36-41
Available from: http://www.indianjpain.org/article.asp?issn=0970-5333;year=2014;volume=28;issue=1;spage=36;epage=41;aulast=Gupta;type=0