Indian Journal of Pain

REVIEW ARTICLE
Year
: 2020  |  Volume : 34  |  Issue : 1  |  Page : 3--7

Central sensitization and its role in chronic pain: What can ketamine do?


Vinita Singh, Jack Williams Shteamer, Jonathan Seth Lowe, Mayson Callaway Augustus 
 Department of Anesthesia, Emory University, Atlanta, GA, USA

Correspondence Address:
Dr. Vinita Singh
1364 Clifton Rd, Emory University Hospital, Atlanta, 30322, GA
USA

Central sensitization plays a crucial role in the development of chronic pain. NMDA receptors play a key role in central sensitization. Ketamine, an NMDA receptor antagonist, can help in refractory chronic pain. Although intravenous is the most common route utilized for delivery of ketamine, other routes such as oral, subcutaneous, topical and intranasal, have been explored. Here we review key research articles regarding the use of ketamine for chronic pain.


How to cite this article:
Singh V, Shteamer JW, Lowe JS, Augustus MC. Central sensitization and its role in chronic pain: What can ketamine do?.Indian J Pain 2020;34:3-7


How to cite this URL:
Singh V, Shteamer JW, Lowe JS, Augustus MC. Central sensitization and its role in chronic pain: What can ketamine do?. Indian J Pain [serial online] 2020 [cited 2020 Aug 6 ];34:3-7
Available from: http://www.indianjpain.org/article.asp?issn=0970-5333;year=2020;volume=34;issue=1;spage=3;epage=7;aulast=Singh;type=0