Indian Journal of Pain

ORIGINAL ARTICLE
Year
: 2013  |  Volume : 27  |  Issue : 3  |  Page : 154--158

Comparison of two concentrations of isobaric intrathecal levobupivacaine for vaginal hysterectomy


Suman Chattopadhyay1, Bibhas Halder2, Gobindo Chandra Saha3, Sukla Karmakar3, Subrata Pahari4 
1 Associate Professor of Anaesthesiology, Medical College, Kolkata, West Bengal, India
2 Postgraduate Trainee in Anaesthesiology, Medical College, Kolkata, West Bengal, India
3 Department of Anaesthesiology, Medical College, Kolkata, West Bengal, India
4 Professor and Head of Anaesthesiology, Medical College, Kolkata, West Bengal, India

Correspondence Address:
Suman Chattopadhyay
BC 103, Salt Lake, Kolkata - 700 064, West Bengal
India

This study was performed to compare the anesthetic efficacy and safety of two concentrations of local anesthetic agent levobupivacaine in patients undergoing vaginal hysterectomy. Forty-four patients of ASA I and II, were randomized to receive an intrathecal injection of one of two local anesthetic solutions. Each patient in Group A (n = 22) received 2 ml of isobaric levobupivacaine 5 mg/ml (10 mg) with 25 μg of fentanyl, while each patient in Group B (n = 22) received 4 ml of isobaric levobupivacaune 2.5 mg/ml (10 mg) with 25 μg of fentanyl. The onset and duration of sensory block at dermatome level T10, maximum upper spread of sensory block, time for two segment regression of sensory block as well as the onset, intensity and duration of motor block were recorded, as were any adverse effects, such as bradycardia, hypotension, nausea, and/or vomiting, etc. The onset of sensory block was similar in both the groups. The onset of motor block was significantly faster in group A compared with that in group B. The duration of sensory and motor blockade was of shorter duration in group B (P < 0.05). However, patients in group A required more use of a vasoactive drug (phenylephrine) compared with group B.


How to cite this article:
Chattopadhyay S, Halder B, Saha GC, Karmakar S, Pahari S. Comparison of two concentrations of isobaric intrathecal levobupivacaine for vaginal hysterectomy.Indian J Pain 2013;27:154-158


How to cite this URL:
Chattopadhyay S, Halder B, Saha GC, Karmakar S, Pahari S. Comparison of two concentrations of isobaric intrathecal levobupivacaine for vaginal hysterectomy. Indian J Pain [serial online] 2013 [cited 2022 Sep 30 ];27:154-158
Available from: https://www.indianjpain.org/article.asp?issn=0970-5333;year=2013;volume=27;issue=3;spage=154;epage=158;aulast=Chattopadhyay;type=0